1. Home
  2. Health
  3. Low Carb Diets

Insulin Resistance

By Laura Dolson, About.com

Updated: November 08, 2006

About.com Health's Disease and Condition content is reviewed by our Medical Review Board

Definition: An insensitivity of the cells to the effects of insulin. Since one of the "jobs" of insulin is to "open the gates" so that the cells will take in glucose (either using it or converting it to storage), blood glucose will stay higher than is healthy unless the body releases more insulin, creating a condition called hyperinsulinemia ("too much insulin in the blood"). High insulin, in turn, can lead to other problems, including weight gain, because high insulin levels tend to facilitate the storage of fat, and makes it more difficult for the body to access fat for energy.

It is estimated that 20-30 percent of the US population is insulin resistant. Insulin resistance is part of the constellation of symptoms called metabolic syndrome, and is considered to be a precursor to Type 2 diabetes (in fact, some doctors give an insulin-resistant person a diagnosis of diabetes, albeit in an early stage). Metabolic syndrome is a risk factor for diabetes, heart disease, and stroke.

More Information about Insulin Resistance
Pronunciation: IN se lin ree SIS tents
Also Known As: pre-diabetes, insulin insensitivity
Common Misspellings: inselin resistence insolin
Examples: According to some studies, people who are insulin resistant respond most positively to a controlled-carbohydrate diet.
Laura Dolson
Guide since 2005

Laura Dolson
Low Carb Diets Guide

Explore Low Carb Diets
About.com Special Features

Learn how you can reduce your your numbers with these nutrition and exercise tips. More >

Keep yourself, and your family, happy and healthy this fall with these tips. More >

We comply with the HONcode standard for trustworthy health information: verify here.
  1. Home
  2. Health
  3. Low Carb Diets
  4. Low Carb 101
  5. Glossary
  6. Insulin Resistance Definition - Glossary Definition for Insulin Resistance

©2009 About.com, a part of The New York Times Company.

All rights reserved.